Chicoric acid ameliorates palmitate-induced sphingosine 1-phosphate signaling pathway in the PBMCs of patients with newly diagnosed type 2 diabetes.

Objective: Sphingosine 1-phosphate (S1P) signaling pathway is involved in the pathogenesis of type 2 diabetes (T2D). So, targeting S1P signaling pathway could be considered as potential therapeutic target for T2D. The aim of this study was to investigate the effects of palmitate and chicoric acid (CA) on S1P signaling pathway in peripheral blood mononuclear cells (PBMCs) from newly diagnosed patients with T2D.

New Pseudachorutes species Tullberg, 1871 (Collembola, Neanuridae) with a key to Iranian species of the genus.

Two new species of the genus Pseudachorutes, namely P. hyrcanicus sp. nov.

/ insight into the effect of titanium dioxide nanoparticle on serum paraoxonase 1 activity in rat.

Serum paraoxonase1 (PON1) has special function in human body organism including the antioxidant and anti-atherogenic properties. In the present study, the effect of TiO nanoparticles on the activity and structure of the PON1 has been evaluated through and methods. After treatments of the rats with different doses of TiO NPs, blood samples were collected and serum PON1 activity was measured by phenylacetate and paraoxon as substrate.

Correlation of acidic mammalian chitinase expression with disease severity in patients with moderate/severe persistent allergic rhinitis.

Aim Of The Study: To assess the level of acidic mammalian chitinase (AMCase) expression and IL-8 in nasal inferior turbinate mucosa in patients with mild and moderate to severe allergic rhinitis (AR).

Material And Methods: Participants in this case-control study were divided into three groups, including patients with moderate and severe persistent allergic rhinitis, cases with mild forms of persistent AR, and control or healthy group. We obtained biopsies of nasal inferior turbinate mucosa from all participants.

Redescription of Ololaelaps tasmanicus (Womersley, 1956) and description of a new species of Ololaelaps Berlese (Acari: Laelapidae) from Iran.

Ololaelaps tasmanicus (Womersley, 1956) is redescribed from the holotype female and two additional female specimens from Australia. Ololaelaps elongatus Babaeian sp. nov.