Publications by authors named "K Kanwar"
Importance: Besides race, little is known about how other social determinants of health (SDOH) affect quality of diabetic eye care.
Objective: To evaluate the association between multiple SDOH and monitoring for diabetic retinopathy (DR) in accordance with clinical practice guidelines (CPGs).
Design, Setting, And Participants: This cohort study was conducted in 11 US medical centers and included adult patients (18-75 years old) with diabetes.
Article Synopsis
- The study aimed to identify predictors of treatment success after increasing the dose of adalimumab in patients with noninfectious uveitis, particularly focusing on the role of anti-adalimumab antibodies.
- A retrospective analysis was conducted comparing treatment outcomes between patients with low to intermediate levels of these antibodies and those who didn't undergo testing, finding that the former had a significantly higher success rate.
- Key results highlighted that patients with panuveitis had lower treatment success rates compared to those with anterior uveitis, emphasizing the importance of antibody testing in treatment planning.
Inflammatory bowel disease (IBD) is a spectrum of diseases characterized by the interplay of the aberrant immune system, genetic factors, environmental factors, and intestinal microbiota, resulting in relapsing inflammation of the gastrointestinal tract. Underlying pro-inflammatory state and immune dysregulation act as a catalyst for increasing the likelihood of developing extraintestinal manifestations, including cardiovascular diseases (CVD) like atherosclerosis, pericarditis, myocarditis, venous and arterial thromboembolism, arrhythmias, despite a lower prevalence of classic CVD risk factors, like high body mass index or dyslipidemia compared to the general population. Chronic inflammation damages endothelium resulting in the recruitment of inflammatory cells, which induce cytotoxicity, lipoprotein oxidation, and matrix degradation, which increases the risk of atherosclerosis.
View Article and Find Full Text PDFAlginate is a major extra polymeric substance in the biofilm formed by mucoid Pseudomonas aeruginosa. It is the main proven perpetrator of lung infections in patients suffering from cystic fibrosis. Alginate lyases are very important in the treatment of cystic fibrosis.
View Article and Find Full Text PDFArticle Synopsis
- The research included a review of 42 patients' medical charts, revealing that 93% exhibited eye problems, with issues like optic nerve/chorioretinal colobomas being the most common.
- The study noted variability in eye conditions with no clear link to specific genetic variants, highlighting the need for more research to understand these associations better.