Blood flow and electrolytes in spinal cord ischemia.

The contribution of reoxygenation-reperfusion injury to ischemic brain damage has been clearly demonstrated but not in the spinal cord. To evaluate this phenomenon in spinal cord ischemia, we measured spinal cord blood flow (SCBF) by [14C]iodoantipyrine and electrolytes in rabbits after 10 or 40 min ischemia followed by 30 min or 4 days recirculation. Ischemia for 10 or 40 min reduced blood flow in the lower lumbar segments L5-L7 (30 ml/100 g/min) to 5 and 10% of control.

Influence of ischemia on retrograde axonal transport in the posterior column fibers of the dog.

The retrograde axonal transport rate in the posterior spinal root was studied by means of the horseradish peroxidase injection in the control dogs and the dogs with the ischemia induced by the lumbal aorta ligature. As the results show, the increase in the retrograde axonal transport rate after 4 h ischemia occured from 141 +/- 6 mm/24 h to 270 +/- 31 mm/24 h. The retrograde transport rate after 7 d ischemia being 137 +/- 7 mm/24h reaches approximately the control values.

Complement consumption in fresh blood sera by double culture of Paramecium caudatum and Aerobacter cloacae compared with survival and stage of disease in some malignant tumors in man.

Using the complement consumption test by double culture of Paramecium caudatum and Aerobacter cloacae (DPA) as antigen we examined blood sera and compared survival rates and stage of disease in 124 patients with carcinoma of cervix uteri, corpus uteri, ovaries and breast. The evidence suggests that bacteria Aerobacter cloacae constitute the proper antigenically effective substances of DPA. The intensity of reaction and therapy the relative titres of antibodies detected by the test were expressed by the amount of complement consumed in the reaction and designated by the abbreviation "NMHD", i.