Publications by authors named "K Kailash"
Thoracic aortic aneurysms (TAAs) are associated with aortic wall remodeling that affects transmural transport or the movement of fluid and solute across the wall. In previous work, we used a Fbln4 (MU) mouse model to investigate transmural transport changes as a function of aneurysm severity. We compared wild-type (WT), MU with no aneurysm (MU-NA), MU with aneurysm (MU-A), and MU with an additional genetic mutation that led to increased aneurysm penetrance (MU-XA).
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- Stiff-person syndrome (SPS) is a rare disorder that makes your muscles really stiff and causes problems with movement, especially in the trunk and close muscles.
- There are different types of SPS, like classic SPS with widespread stiffness and partial SPS which affects just some limbs.
- A young man showed signs of SPS with a forward-leaning posture and involuntary movements, and doctors used tests like MRI and blood work to confirm the diagnosis and treat him.
Article Synopsis
- * Research on mice shows that the adaptability of arterial material properties changes between types of arteries, with the ascending aorta being more flexible than the carotid artery as they age.
- * Findings indicate that sex differences influence how arterial properties change, and strong correlations exist between ECM composition and biomechanical parameters, potentially informing personalized treatments for arterial stiffening.