Prediction of Seizure Outcome Using Combinations of Four Noninvasive Presurgical Modalities in Magnetic Resonance Imaging-negative Focal Intractable Epilepsy.

In focal epilepsy cases, precise identification and resection of the epileptogenic zone increase the likelihood of achieving a seizure-free outcome. Nevertheless, localizing the source of epilepsy in magnetic resonance imaging-negative epilepsy cases presents significant challenges for clinicians. In this study, we evaluated the diagnostic efficacy and impact on the seizure outcome by using 4 noninvasive modalities, including scalp video electroencephalography, magnetoencephalography, fluorodeoxyglucose-positron emission tomography, and iomazenil single-photon emission computed tomography, in a cohort of patients with magnetic resonance imaging-negative focal epilepsy who underwent resective surgery.

[A Case of Esophageal Perforation Caused by Metallic Stent Placement after Long-Term Chemotherapy for Advanced Gastric Cancer].

A 72-year-old man had been undergoing chemotherapy for advanced gastric cancer for over 4 years. He presented with dysphagia, and esophagogastroduodenoscopy(EGD)revealed esophageal stricture due to tumor growth. Subsequently, he underwent placement of a partially covered esophageal stent(HANAROSTENT® Esophagus, M.

Elotuzumab-mediated ADCC with Th1-like Vγ9Vδ2 T cells to disrupt myeloma-osteoclast interaction.

Multiple myeloma (MM) cells and osteoclasts (OCs) activate with each other to cause drug resistance. Human Th1-like Vγ9Vδ2 (γδ) T cells, important effectors against tumors, can be expanded and activated ex vivo by the aminobisphosphonate zoledronic acid in combination with IL-2. We previously reported that the expanded γδ T cells effectively targeted and killed OCs as well as MM cells.

Risk factors for wound dehiscence after surgery for epilepsy.

Objective: Wound dehiscence following craniotomy is a complication for which patients are subjected to additional procedures to achieve wound closure. During surgery for epilepsy, a craniotomy is performed at various sites to cure or palliate seizures in patients with intractable epilepsy. Collaborations between medicine and engineering have provided many surgical devices and materials for various stages of craniotomy, from skin incision to wound closure.