Invasive aspergillosis (IA) represents a common form of fungal infection caused by various species of that most frequently affect immunocompromised patients. Typically, this disease occurs preferentially in high-risk groups including patients infected with the human immunodeficiency virus (HIV), patients with leukemia, patients with autoimmune diseases, and organ transplant patients undergoing medical immunosuppression. Considered the second most common cause of opportunistic fungal infection in humans after , this pathogen predominantly affects the lungs, but it may also spread by a hematogenous route to various organs and have a heterogeneous presentation.
View Article and Find Full Text PDFLeptospirosis is a bacterial zoonosis that affects both humans and animals worldwide. Currently, it is known that cats may be susceptible to infection. This study aims to investigate the presence of anti-Leptospira spp.
View Article and Find Full Text PDFThe execution of cognitive functions requires coordinated circuit activity across different brain areas that involves the associated firing of neuronal assemblies. Here, we tested the circuit mechanism behind assembly interactions between the hippocampus and the medial prefrontal cortex (mPFC) of adult rats by recording neuronal populations during a rule-switching task. We identified functionally coupled CA1-mPFC cells that synchronized their activity beyond that expected from common spatial coding or oscillatory firing.
View Article and Find Full Text PDFBackground: High ratio of the carbon dioxide veno-arterial difference to the oxygen arterial-venous difference (PCO/CO) is associated with fluid bolus (FB) induced increase in oxygen consumption (VO). This study investigated whether PCO/CO was associated with decreases in blood-lactate levels FB in critically ill patients with hyperlactatemia.
Methods: This prospective observational study examined adult patients in the intensive care unit (ICU) with lactate levels > 1.