Empowering African Expertise: Enhancing Safety Data Integration and Signal Detection for COVID-19 Vaccines Through the African Union Smart Safety Surveillance Joint Signal Management Group.

Introduction: The COVID-19 pandemic accelerated new vaccine development. Limited safety data necessitated robust global safety surveillance to accurately identify and promptly communicate potential safety issues. The African Union Smart Safety Surveillance (AU-3S) program established the Joint Signal Management (JSM) group to support identification of potential vaccine safety concerns in five pilot countries (Ethiopia, Ghana, Kenya, Nigeria, South Africa), accounting for approximately 35% of the African population.

On the Role of Epigenetic Modifications of HPA Axis in Post Traumatic Stress Disorder (PTSD) and Resilience.

Stress is a fundamental adaptive response mediated by the amygdala and Hypothalamus-Pituitary-Adrenal (HPA) axis. Extreme or chronic stress, however, can result in a multitude of neuropsychiatric disorders, including anxiety, paranoia, bipolar disorder (BP), major depressive disorder (MDD), and Post-Traumatic Stress Disorder (PTSD). Despite widespread exposure to trauma (70.

Excellent acetone sensing enabled by tunable metal organic framework derived TiO nanodisks.

Annealing plays a crucial role for in enhancing the gas sensing properties of MOF-derived TiO (MIL-125). Generally, TiO transforms into different polymorphs (anatase, rutile, and brookite) during annealing, each with unique crystal structures and gas sensing properties. The aim of this research was to investigate the impact of annealing (500-650 °C) on the properties of MIL-125, which had not been previously studied.

Synergistic effect of Zr MOF modified functionalized carbon nano fibres for determination of tert-butylhydroquinone in food samples.

In modern life, people often neglect to consider their eating habits. Antioxidants are primarily used as food additives due to their stability and low toxicity. TBHQ is a commonly used antioxidant in food products as an additive.

HPV vaccine hesitancy among parents and caregivers of adolescents in Northern Nigeria.

Background: The recent introduction of the HPV vaccine into Nigeria's routine immunization schedule has brought parental vaccine hesitancy to the forefront. This cross-sectional study, conducted in Kano State, a region with historically low immunization rates, is crucial in assessing the level of parental hesitancy and uncovering its determinants, potentially informing future public health policies.

Methods: The participants were a representative sample of parents or caregivers of children aged 9-14 years ( = 1071) in Kano State and were selected via a multi-stage sampling method.