Unraveling the Role of Functional Groups of Terephthalate in Enhancing the Electrochemical Oxygen Evolution Reaction of Nickel-Organic Framework Nanoarrays.

The platelike nickel-terephthalate-type metal-organic framework nanoarrays (Ni-BDC NAs) on carbon cloth are obtained by employing agaric-like Ni(OH) NAs as sacrificial templates. The microenvironment of Ni-BDC NAs is modulated by various neighboring functional groups (-NH, -NO, and -Br) on the carboxylate ligand, exerting minimal destructive effects on the structure and morphology of Ni-BDC NAs. The electrochemical oxygen evolution reaction (OER) of Ni-BDC-NH NAs, Ni-BDC-NO NAs, and Ni-BDC-Br NAs exhibited a significant enhancement compared to that of Ni-BDC NAs alone, as evidenced by both experimental and theoretical assessments.

Association between serum uric acid-to-high-density lipoprotein cholesterol ratio and metabolic dysfunction-associated steatotic liver disease among Chinese children with obesity.

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the most prevalent chronic liver diseases worldwide. The serum uric acid-to-high-density lipoprotein cholesterol ratio (UHR) has been recognized as a novel marker for metabolic diseases, including MASLD. However, all previous studies were performed in adults.

CD4-Derived Double-Negative T Cells Ameliorate Alzheimer's Disease-Like Phenotypes in the 5×FAD Mouse Model.

Background: Alzheimer's disease (AD) is a debilitating neurodegenerative disorder that is difficult to predict and is typically diagnosed only after symptoms manifest. Recently, CD4 T cell-derived double-negative T (DNT) cells have shown strong immuno-regulatory properties in both in vitro and in vivo neuronal inflammation studies. However, the effectiveness of DNT cells in treating on AD are not yet fully understood.

Global, regional, and national burden of young COPD, 1990-2021, with forecasts to 2050: a systematic analysis for the global burden of disease study 2021.

Background: Young chronic obstructive pulmonary disease (COPD) refers to people with COPD between the ages of 20 and 50 years. Current epidemiological studies focus on local geography, and there is a lack of global-level analysis. This study provides in-depth analyses of the disease burden of young COPD at global, regional, and national levels.