The Perfect Storm: A Case of Rapid-Onset Obesity With Hypoventilation, Hypothalamic, Autonomic Dysregulation, Neuroendocrine Tumor (ROHHADNET) With Heart Failure, Narcolepsy, and a Rare Location of a Pelvic Neuroendocrine Tumor.

Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome is a rare disease of concurrent respiratory dysfunction and autonomic dysregulation with endocrine abnormalities. ROHHADNET includes ROHHAD plus coexisting neuroendocrine tumors (NETs). We describe an eight-year-old boy, who originally presented at four years of age with rapid weight gain and hyperhidrosis and who developed mild obstructive sleep apnea (OSA).

Topographical structures in planting design of living walls affect their ability to immobilise traffic-based particulate matter.

Traffic-generated particulate matter (PM) pollution is a serious threat to human health and the environment, especially in urban settings. Recent studies have revealed the effectiveness of living walls in the reduction of this pollution; these systems use variable planting designs and their topographical dynamics might have an impact on PM dry deposition. This present study, employing an experimentally manipulable living wall system using box (Buxus sempervirens L.

Quantification of the traffic-generated particulate matter capture by plant species in a living wall and evaluation of the important leaf characteristics.

Traffic-generated particulate matter (PM) is a significant fraction of urban PM pollution and little is known about the use of living walls as a short-term strategy to reduce this pollution. The present study evaluated the potential of twenty living wall plants to reduce traffic-based PM using a living wall system located along a busy road in Stoke-on-Trent, UK. An Environmental Scanning Electron Microscope (ESEM) and ImageJ software were employed to quantify PM accumulation on leaves (PM, PM and PM) and their elemental composition was determined using Energy Dispersive X-ray (EDX).

High-level semi-synthetic production of the potent antimalarial artemisinin.

In 2010 there were more than 200 million cases of malaria, and at least 655,000 deaths. The World Health Organization has recommended artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated malaria caused by the parasite Plasmodium falciparum. Artemisinin is a sesquiterpene endoperoxide with potent antimalarial properties, produced by the plant Artemisia annua.