A Blissful Role of Probiotic Therapy as an Adjunct to Periodontal Surgery in the Treatment of Periodontitis.

Background Periodontitis is a chronic inflammatory disease that alters the alveolar bone structure, requiring treatment ranging from non-surgical to surgical periodontal therapies based on its severity. Surgical interventions, such as the modified Widman flap procedure and the open flap technique combined with methods like platelet-rich fibrin (PRF), guided tissue regeneration (GTR), and bone grafts, aim to reduce periodontal pockets and regenerate lost tissues. The presence of pathogenic bacteria and the absence of beneficial bacteria contribute to periodontitis, with probiotics-live microorganisms that offer health benefits emerging as a promising adjunct in periodontal therapy.

Insights on therapeutic approaches of natural anti-Alzheimer's agents in the management of Alzheimer's disease: A future perspective.

In the current scenario, Alzheimer's disease is a complex, challenging, and arduous health issue, and its prevalence, together with comorbidities, is accelerating around the universe. Alzheimer's disease is becoming a primary concern that significantly impacts an individual's status in life. The traditional treatment of Alzheimer's disease includes some synthetic drugs, which have numerous dangerous side effects, a high risk of recurrence, lower bioavailability, and limited treatment.

A Cross-talk between Nanomedicines and Cardiac Complications: Comprehensive View.

Background: Cardiovascular Diseases (CVDs) are the leading cause of global morbidity and mortality, necessitating innovative approaches for both therapeutics and diagnostics. Nanoscience has emerged as a promising frontier in addressing the complexities of CVDs.

Objective: This study aims to explorethe interaction of CVDs and Nanomedicine (NMs), focusing on applications in therapeutics and diagnostics.

Does Adopting Western Low-density Lipoprotein Cholesterol Targets Expose Indians to a Higher Risk of Cardiovascular Events? Expert Opinion From the Lipid Association of India.

Adverse cardiovascular (CV) events have declined in Western countries due at least in part to aggressive risk factor control, including dyslipidemia management. The American and European (Western) dyslipidemia treatment guidelines have contributed significantly to the reduction in atherosclerotic cardiovascular disease (ASCVD) incidence in the respective populations. However, their direct extrapolation to Indian patients does not seem appropriate for the reasons described below.

Gender differences in the management and outcomes of acute coronary syndrome in indians: A systematic review and meta-analysis.

Background: Gender differences in acute coronary syndrome (ACS) outcomes have been noted in global data, which however did not analyse Indian data. No prior systematic review and meta-analysis (SRM) has addressed this important aspect of gender bias in Indian women with ACS. Hence this SRM aimed to address this knowledge gap.