Publications by authors named "K K Kozlov"
Aim: To evaluate the efficacy of the antiviral drug riamilovir (trade name - «Triazavirin») for the prevention of SARS-CoV-2 infection (COVID-19) and other acute respiratory viral infections in young people from organized groups.
Materials And Methods: The study involved 386 individuals aged 18-22 years: 199 received riamilovir at a daily dose of 250 mg for 15 days, while 187 did not receive prophylactic drugs. For 30 days, disease occurrence was monitored among volunteers.
Article Synopsis
- Human pluripotent stem cells (hPSCs) can differentiate into any adult tissue, making them important for regenerative medicine and research into factors affecting their growth and characteristics.
- The study analyzed the migration patterns of three hPSC cell lines (AD3, CaSR, and H9) through bright-field imaging, focusing on their "good" and "bad" morphological phenotypes.
- Results showed that migration speed varied based on the cell line and growth environment, with notable differences in migration behavior between "good" and "bad" colonies, particularly in specific culture conditions.
Aim: To evaluate the clinical effectiveness, safety and compare the incidence of hospitalization during treatment with antiviral drugs with a direct mechanism of action (riamilovir and umifenovir) in people with acute respiratory viral infections (ARVI) in an outpatient setting.
Materials And Methods: The study included 150 outpatients with ARVI aged 18-27 years: 50 patients received riamilovir 250 mg 3 times a day for 5 days, the second group included 50 patients who received umifenovir 200 mg 4 times a day for 5 days, 50 individuals received only pathogenetic treatment.
Results: The use of direct-acting antiviral drugs was characterized by the least severity of pain and aches in the body, general weakness, and in the group of patients receiving riamilovir, the lowest severity of rhinitis, cough, and the lowest morning body temperature were recorded compared to other groups.
The chickpea plays a significant role in global agriculture and occupies an increasing share in the human diet. The main aim of the research was to develop a model for the prediction of two chickpea productivity traits in the available dataset. Genomic data for accessions were encoded in Artificial Image Objects, and a model for the thousand-seed weight (TSW) and number of seeds per plant (SNpP) prediction was constructed using a Convolutional Neural Network, dictionary learning and sparse coding for feature extraction, and extreme gradient boosting for regression.
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- Elderly patients who undergo cholecystectomy need careful monitoring due to age-related bodily changes that can lead to complications, especially fatty liver degeneration.
- A study of 159 men showed a link between increased body mass index and loss of beneficial gut bacteria, indicating a potential risk for fatty liver issues in elderly individuals post-surgery.
- The researchers created a predictive algorithm that can accurately identify a high risk of fatty liver degeneration in these patients with at least 75% accuracy, based on specific key indicators.