Publications by authors named "K K Holzer"
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View Article and Find Full Text PDFResults of F-choline and C-methionine positron emission tomography/computed tomography for the preoperative localization of hyperfunctional parathyroid glands in primary hyperparathyroidism.
Surgery
January 2025
Background: Preoperative localization of hyperfunctioning parathyroid glands in primary hyperparathyroidism is essential for successful parathyroid surgery, particularly in patients with previous negative imaging or reoperations.
Methods: A multicenter registry study was performed in 776 patients with primary hyperparathyroidism from 53 hospitals in Germany and Austria who underwent parathyroid surgery after preoperative F-choline or C-methionine positron emission tomography/computed tomography (PET/CT).
Results: In 683 of 776 patients (88%) (78% female, aged 15-86 years), primary hyperparathyroidism was caused by a single-gland parathyroid adenoma.
Introduction: Oncologic surgeries are common and rates of depression and anxiety are high in the peri-operative period, potentially interfering with successful recovery.
Methods: We conducted a narrative review and meta-analysis focusing on randomised controlled trials evaluating the effect of peri-operative mental health interventions on anxiety and/or depression in adult patients having oncological surgery. The review included studies published in the last 5 years, identified through EMBASE with no pre-specified criteria for the type of comparison or outcome.
Background: Postoperative anxiety and depression can negatively affect surgical outcomes and patient wellbeing. This study aimed to quantify the incidence of postoperative worsening anxiety and depression symptoms and to identify preoperative predictors of these conditions.
Methods: This prospective, observational cohort study included 1168 patients undergoing surgery lasting >1 h with overnight admission at a university-affiliated quaternary referral centre.
Article Synopsis
- - The perioperative period can cause significant anxiety and depression for patients due to fears about surgery and potential complications, highlighting the need for tailored psychological support during this time.
- - A systematic review of 25 studies found that compassion-based interventions, focusing on improved communication and emotional support from healthcare professionals, reduced anxiety in 72% of cases and also showed positive impacts on patient satisfaction and postoperative outcomes.
- - While the results are promising, the review noted limitations, such as unclear methods in many studies and a smaller number of studies suitable for deeper analysis, suggesting that more focused research is needed to solidify these findings in routine patient care.