Publications by authors named "K Juarez-Moreno"

Our work describes the green synthesis of silver sulfide nanoparticles (AgS NPs) and their formulation into polycaprolactone fibers (PCL), aiming to improve the multifunctional biological performance of PCL membranes as scaffolds. For this purpose, an extract of rosemary () was employed as a reducing agent for the AgS NPs, obtaining irregular NPs and clusters of 5-60 nm, with a characteristic SPR absorption at 369 nm. AgS was successfully incorporated into PCL fibers by electrospinning using heparin (HEP) as a stabilizer/biocompatibility agent, obtaining nanostructured fibers with a ca.

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Article Synopsis
  • Nanotechnology, particularly silver nanoparticles (AgNPs), shows promise in improving cancer treatments, especially in overcoming chemotherapy resistance and reducing side effects from toxic drugs.
  • Research demonstrated that combining AgNPs with the drug tamoxifen leads to a synergistic effect that not only increases cell death in breast cancer cells but also prevents their migration and boosts reactive oxygen species production.
  • Despite these effects, the combination of AgNPs and tamoxifen exhibited minimal genotoxicity, and both types of breast cancer cells showed heightened expression of genes linked to cell death and oxidative stress, indicating potential for further exploration in cancer therapy.
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For the first time, this study shows the nanoarchitectonic process to obtain an acetogenin-enriched nanosystem (AuNPs-Ac) using an aqueous extract fromMill (ACM) composed of gold nanoparticles embedded in an organic matrix that acts as stabilizing agent and presents anti-inflammatory activity and cytotoxical effect against HepG2 cell line, promoting apoptosis. The synthesis of AuNPs-Ac was confirmed by x-ray diffraction analysis, showing metallic gold as the only phase, and the scanning transmission microscope showed an organic cap covering the AuNPs-Ac. Fourier-transformed infrared suggests that the organic cap comprises a combination of different annonaceous acetogenins, alkaloids, and phenols by the presence of bands corresponding to aromatic rings and hydroxyl groups.

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The antioxidant capabilities of nanoparticles are contingent upon various factors, including their shape, size, and chemical composition. Herein, novel Nd-doped CeO nanoparticles were synthesized and the neodymium content was varied to investigate the synergistic impact on the antioxidant properties of CeO nanoparticles. Incorporating Nd induced changes in lattice parameters and significantly altered the morphology from nanoparticles to nanorods.

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This study used a sonochemical synthesis method to prepare (La, Sm)-doped ZnO nanoparticles (NPs). The effect of incorporating these lanthanide elements on the structural, optical, and morphological properties of ZnO-NPs was analyzed. The cytotoxicity and the reactive oxygen species (ROS) generation capacity of ZnO-NPs were evaluated against breast (MCF7) and colon (HT29) cancer cell lines.

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