Publications by authors named "K Johanning"
Background: Currently, the data regarding the impact of prehospital postcardiac arrest anesthesia on target hemodynamic and ventilatory parameters of early postresuscitation care and recommendations on its implementation are rare. The present study examines the incidence and impact of prehospital postcardiac arrest anesthesia on hemodynamic and ventilatory target parameters of postresuscitation care.
Methods: In this multicentre observational study between 2019 and 2021 unconscious adult patients after out-of-hospital-cardiac arrest with the presence of a return-of-spontaneous circulation until hospital admission were included.
Bioaccumulation predictions can be substantially improved by combining in vitro metabolic rate measurements derived from rainbow trout hepatocytes and/or hepatic S9 fractions with quantitative structure-activity relationship (QSAR) modeling approaches. Compared with in vivo testing guidelines Organisation for Economic Co-operation and Development (OECD) 305 and Office of Chemical Safety and Pollution Prevention (OCSPP; an office of the US Environmental Protection Agency) 850.1730, the recently adopted OECD test guidelines 319A and 319B are in vitro approaches that have the potential to provide a time- and cost-efficient, humane solution, reducing animal use while addressing uncertainties in bioaccumulation across species.
View Article and Find Full Text PDFBackground: The aim of this study was to examine the impact of COVID-19 on the response rate of community-first-responders (CFR) and other out-of-hospital-cardiac-arrest (OHCA) outcomes using the smartphone-first-responder-system (SFRS) "Mobile Retter."
Methods: All adult non-traumatic OHCA in the district of Gütersloh between 01.01.
Article Synopsis
- An investigation was conducted to assess the impact of midazolam used for post-arrest sedation on achieving essential post-resuscitation care targets and the risk of hemodynamic complications in patients who experienced out-of-hospital cardiac arrest (OHCA).
- The study reviewed emergency rescue missions from 2019-2021 and found that among patients with return of spontaneous circulation (ROSC), those receiving midazolam were more likely to meet recommended targets for blood pressure, oxygen levels, and carbon dioxide levels compared to those who did not receive sedation.
- The results suggest that using midazolam during the pre-hospital phase improves the chances of meeting critical oxygenation and ventilation goals in post-arrest patients, indicating its potential benefit in
Background: This study evaluates the implementation of postcardiac-arrest-sedation (PCAS) and -care (PRC) by prehospital emergency physicians in Germany.
Materials And Methods: Analysis of a web-based survey from October to November 2022. Questions were asked about implementation, medications used, complications, motivation for implementing or not implementing PCAS, and measures and target parameters of PRC.