Publications by authors named "K Jalava"
Article Synopsis
- The DREAMM project aimed to reduce deaths from HIV-related central nervous system (CNS) infections in three African countries through improved diagnostic and treatment strategies.
- It implemented a stepwise intervention including rapid testing and adherence to WHO guidelines while enhancing hospital care via education and systemic improvements.
- By comparing 2-week mortality rates across phases, the project enrolled 501 participants between 2016 and 2021 and focused on those with advanced HIV, highlighting the need for effective management in HIV-related CNS conditions.
Background: Appendicectomy remains the standard treatment for appendicitis. No international consensus exists on the surgical urgency for acute uncomplicated appendicitis, and recommendations vary from surgery without delay to surgery within 24 h. Longer in-hospital delay has been thought to increase the risk of perforation and further morbidity.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the emergence of a specific lineage of Shiga toxin-producing E. coli (STEC) O157:H7, known as lineage IIc, responsible for foodborne illnesses in England, and analyzes its domestic and non-domestic reservoirs along with patient exposures.
- Researchers conducted a genomic epidemiological analysis on 925 STEC O157:H7 samples from patients in England between June 2015 and December 2020, utilizing whole-genome sequencing and various data sources to map transmission dynamics.
- Findings revealed the presence of two domestic and four non-domestic clades of lineage IIc, with non-domestic transmissions being more prevalent; patients with domestic infections had significant exposure to fresh produce and livestock, indicating potential
Seven major food- and waterborne norovirus outbreaks in Western Finland during 2014-2018 were re-analysed. The aim was to assess the effectiveness of outbreak investigation tools and evaluate the Kaplan criteria. We summarised epidemiological and microbiological findings from seven outbreaks.
View Article and Find Full Text PDF