Publications by authors named "K Jakuszko"

Article Synopsis
  • The study aimed to analyze patients with eosinophilic granulomatosis with polyangiitis (EGPA) from the POLVAS registry based on their ANCA status and when they were diagnosed, and compare them to patients with granulomatosis with polyangiitis (GPA) who have elevated eosinophil levels.
  • The results indicated that while ANCA-positive and ANCA-negative EGPA patients had similar clinical characteristics, ANCA-negative patients experienced more cardiovascular issues. Moreover, patients diagnosed before 2012 were generally younger and exhibited higher eosinophil counts and more frequent ENT and cardiovascular symptoms.
  • The researchers developed a model to differentiate between EGPA and GPA with elevated eosinophils, achieving high
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Background: Molnupiravir demonstrated an in vitro antiviral activity against positive-sense RNA viruses, including SARS-CoV-2. The study aimed to present the results of outpatient molnupiravir use in kidney transplant recipients and hemodialysis patients during the first months of 2022 in Poland.

Methods: The retrospective observational cohort study at one kidney transplant center included 36 patients diagnosed with COVID-19 with an automated nucleic acid amplification test on nasopharyngeal swab specimens.

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Objective: Human milk contains antibodies against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which may serve as a protective factor through passive immunization in infants. The objective of this study was to measure the levels of anti-SARS-CoV-2 IgG and IgA in human milk and serum after a SARS-CoV-2 infection.

Design: Breast milk and serum samples from 72 lactating mothers with confirmed SARS-CoV-2 asymptomatic or symptomatic infection were collected 1-229 days after the onset of clinical symptoms related to COVID-19.

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Focal segmental glomerulosclerosis (FSGS) involves podocyte injury. In patients with nephrotic syndrome, progression to end-stage renal disease often occurs over the course of 5 to 10 years. The diagnosis is based on a renal biopsy.

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Objectives: The study aimed to characterise the Polish population of (ANCA)-associated vasculitides (AAV) with respiratory involvement (RI), in comparison to the subgroup without lung manifestations and the other cohorts.

Methods: Retrospective analysis of the Polish population of AAV with RI was conducted, based on data from the POLVAS registry. Standard descriptive statistics, χ2 test, and Mann-Whitney U test were used to perform comparisons.

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