Effects of mistletoe (Viscum album L.) extracts Iscador on cell cycle and survival of tumor cells.

The molecular and cellular mechanisms by which mistletoe (Viscum album L.) extracts exert cytotoxic and immunomodulatory anti-tumoral effects are largely unknown. In this study the hypothesis that Iscador preparations induce tumor regression by cell cycle inhibition and/or interference with apoptotic signaling pathways in cancer cells was investigated.

Exploratory study on the effects of treatment with two mistletoe preparations on chronic hepatitis C.

Twenty-one patients with chronic hepatitis C were treated with a mistletoe preparation as monotherapy (either Iscador or Abnoba viscum) during one year. The treatment was well tolerated. Patients entering the study with elevated transaminases had a significant improvement, both for AST (aspartate aminotransferase) (p = 0.

Differential effects of Viscum album extract IscadorQu on cell cycle progression and apoptosis in cancer cells.

Extracts from European mistletoe or Viscum album L. have been reported to exert cytotoxic and immunomodulatory effects in vitro and in vivo. The mechanism of this anti-tumoral activity is however, largely unknown.

Iscador Qu for chronic hepatitis C: an exploratory study.

Five patients with chronic hepatitis C were treated for one year with the herbal immunomodulatory agent Iscador (Weleda, Schwäbisch Gmünd Germany). Two patients showed 6-20 fold decreases in viral load and normalisation of liver inflammation. The treatment was well tolerated; no serious side effects were observed.

Measurement of proliferation indices in non Hodgkin's lymphoma--is it useful?

In this review we discuss the possible value of additional information concerning growth characteristics of NHL's for the prognosis of the individual patient. Techniques for measuring cell cycle kinetic parameters (e.g.