Publications by authors named "K J Schmitz"

Article Synopsis
  • - The MoVEonUp Trial is examining a home-based program to reduce falls and urinary incontinence in older women, specifically those aged 70 and older who suffer from urgency urinary incontinence (UUI), a condition affecting 40% of this demographic.
  • - This study involves 314 participants who will be divided into an intervention group receiving a multicomponent program (including strength and balance training, bladder training, and home safety assessments) and a control group getting educational materials on fall prevention.
  • - The effectiveness of this intervention will be measured over 12 months by assessing outcomes related to falls, urinary symptoms, physical function, and mobility to see if it successfully reduces falls and improves incontinence among the participants.
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Drug-resistant tuberculosis infections are a major threat to global public health. The essential mycobacterial ClpC1P1P2 protease has received attention as a prospective target for novel antibacterial therapeutics. However, efforts to probe its function in cells are constrained by our limited knowledge of its physiological proteolytic repertoire.

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Article Synopsis
  • - The National Accreditation Program for Breast Centers (NAPBC) initiated a quality collaborative to evaluate the time between breast cancer screening and treatment, analyzing data from 2019 to 2021.
  • - A total of 373 accredited centers participated, with 311 providing complete metrics, revealing that the actual treatment time exceeded expectations across various intervals, from screening to diagnosis and biopsy to treatment.
  • - Findings indicated discrepancies in treatment timing, with factors like higher case volumes and dedicated breast surgeons linked to longer intervals, highlighting the need for further investigation into quality measures across different centers.
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Purpose: Despite exercise's known benefits for cancer patients, little is understood about combining it with immune checkpoint inhibitors (ICI). This study aims to assess the feasibility and acceptability of a personalized physical activity program for cancer patients on ICI treatment and to investigate its effects on quality of life, ICI-related side effects, fatigue, and emotional symptoms.

Methods: This prospective study was conducted across eight cancer practices in a joint network in Brazil.

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