Publications by authors named "K J Rohner"
Outcome of immunosuppression in children with IgA vasculitis-related nephritis.
Nephrol Dial Transplant
July 2024
Article Synopsis
- Immunoglobulin A vasculitis with nephritis (IgAVN) is the most common vasculitis in children, and this study aimed to analyze clinical outcomes, treatments, and risk factors in a large cohort of 1148 children diagnosed with the condition.
- The retrospective analysis revealed that poorer outcomes were associated with factors like older age, lower kidney function at onset, hypertension, and certain kidney damage features, but no specific treatment was found to be more effective than others.
- The study concluded that there is a need for further research and clinical trials to determine effective treatments and improve health outcomes for children with IgAVN.
Background: Children with non-refluxing primary megaureter are mostly managed by a watchful approach with close follow-up and serial imaging.
Objectives: This systematic review and meta-analysis aimed to determine whether there is sufficient evidence to support the current non-surgical management strategy in these patients.
Data Sources: A comprehensive search including electronic literature databases, clinical trial registries, and conference proceedings was performed.
Background: Knowledge of the baseline risk of febrile urinary tract infections in patients with primary non-refluxing megaureter can help clinicians to make informed decisions for offering continuous antibiotic prophylaxis.
Objective: The primary objective of this systematic review was to determine the pooled prevalence of febrile urinary tract infections in patients with primary non-refluxing megaureter selected for primary non-surgical management independent of associated attributed risk factors at initial presentation in order to assess the value of continuous antibiotic prophylaxis.
Methods: MEDLINE, EMBASE, and Cochrane Controlled Trials Register electronic databases were searched for eligible studies without language and time restriction.