Publications by authors named "K J Lyon"
Background Context: Ropivacaine-Epinephrine-Clonidine-Ketorolac (RECK) cocktail can improve pain control in patients undergoing lumbar decompression. Given the aging population, rising healthcare costs, the opioid epidemic, and associations of acute pain control with long-term opioid use, effective opioid-sparing analgesia following spinal fusion surgery may impart societal benefits.
Purpose: We aimed to investigate whether RECK was an effective local anesthetic for patients undergoing posterior spinal fusion.
Article Synopsis
- Recent advances in fluorescence microscopy allow for real-time observation of individual RNA translation dynamics in living cells using multiple colors.
- The described protocol enables simultaneous imaging of two open reading frames on a single reporter RNA that are offset from each other.
- This method provides detailed insights into frameshifting dynamics and efficiency, measured at the single-RNA level, by examining specific frameshift stimulatory sequences.
Article Synopsis
- Community engagement (CE) improves the ethics, rigor, and impact of research, especially when integrating Indigenous and western research systems.
- The Multi-site Implementation Evaluation of Tribal Home Visiting (MUSE) utilized a community-engaged approach to analyze home-visiting programs in 17 Indigenous communities across the U.S.
- The paper outlines MUSE's CE methods, highlights its key outcomes, discusses barriers faced, and shows that effective CE is both feasible and beneficial for multisite studies with Indigenous communities.
There are millions of river barriers worldwide, ranging from wooden locks to concrete dams, many of which form associated impoundments to store water in small ponds or large reservoirs. Besides their benefits, there is growing recognition of important environmental and social trade-offs related to these artificial structures. However, global datasets describing their characteristics and geographical distribution are often biased towards particular regions or specific applications, such as hydropower dams affecting fish migration, and are thus not globally consistent.
View Article and Find Full Text PDFThe optimization and detailed characterization of gastrointestinal organoid models require advanced methods for analyzing their luminal environments. This paper presents a highly reproducible method for the precise measurement of pH within the lumina of 3D human gastric organoids via micromanipulator-controlled microelectrodes. The pH microelectrodes are commercially available and consist of beveled glass tips of 25 µm in diameter.
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