Publications by authors named "K J Hodgson"
Iron(IV)-oxo intermediates found in iron enzymes and artificial catalysts are competent for H atom abstraction in catalytic cycles. For = 2 intermediates, both axial and equatorial approaches are well-established. The mechanism for = 1 sites is not as well understood: an equatorial approach is more energetically favorable, and an axial approach requires crossing from the = 1 to the = 2 surface.
View Article and Find Full Text PDFArticle Synopsis
- - The study evaluates if major management guidelines for extremely preterm infants are effectively applicable to those born before 25 weeks' gestation by reviewing three significant sets of guidelines and their referenced studies.
- - Out of 519 studies analyzed, only about 14.5% of infants were under 25 weeks, with a significant portion of the research, 37.8%, not including any infants from this critical group.
- - The findings conclude that infants born before 25 weeks gestation are underrepresented in the data driving clinical guidelines, highlighting the need for more focused research on this vulnerable population.
Therapeutic vaccination can harness the body's cellular immune system to target and destroy cancerous cells. Several treatment options are available to eliminate pre-cancerous and cancerous lesions caused by human papillomaviruses (HPV), but may not result in a long-term cure. Therapeutic vaccination may offer an effective, durable, and minimally intrusive alternative.
View Article and Find Full Text PDFProstate cancer is a lethal solid malignancy and a leading cause of cancer-related deaths in males worldwide. Treatments, including radical prostatectomy, radiotherapy, and hormone therapy, are available and have improved patient survival; however, recurrence remains a huge clinical challenge. Enzalutamide is a second-generation androgen receptor antagonist that is used to treat castrate-resistant prostate cancer.
View Article and Find Full Text PDFPredicting extubation failure in preterm infants using lung ultrasound: a diagnostic accuracy study.
Arch Dis Child Fetal Neonatal Ed
August 2024
Article Synopsis
- A study was done to see how well lung ultrasound (LUS) can predict if preterm babies under 32 weeks will need to be put back on a breathing machine after being taken off.
- The results showed that LUS wasn't very good at predicting this for most babies, but it worked better for extremely preterm babies (born before 28 weeks) and those who were very young (under 72 hours old).
- Researchers think they should study babies who are at high risk of needing to go back on the machine and maybe use simpler ways to check their lungs in the future.