Publications by authors named "K J Grant"
Human and non-human primate studies clearly implicate the dorsolateral prefrontal cortex (dlPFC) as critical for advanced cognitive functions. It is thought that intracortical synaptic architectures within the dlPFC are the integral neurobiological substrate that gives rise to these processes. In the prevailing model, each cortical column makes up one fundamental processing unit composed of dense intrinsic connectivity, conceptualized as the "canonical" cortical microcircuit.
View Article and Find Full Text PDFImplementing and evaluating a project to enable and encourage Caribbean data-sharing.
Rev Panam Salud Publica
December 2024
The CaribData project, funded by the Inter-American Development Bank and implemented by The University of the West Indies, aims to enhance data-handling, -sharing and reuse capabilities in the Caribbean. The project focuses on four main objectives: developing an online data-handling platform, creating a sustainable training and mentoring program, launching a data communication initiative and conducting data availability audits. To evaluate its progress, CaribData integrates two implementation science frameworks, RE-AIM (for Reach, Effectiveness, Adoption, Implementation, Maintenance) and the Consolidated Framework for Implementation Research.
View Article and Find Full Text PDFEnergetic activity for depression in young people aged 13-17 years: the READY feasibility RCT.
Health Technol Assess
December 2024
Article Synopsis
- The study aims to evaluate the feasibility of an exercise intervention for young people aged 13-17 with mild to moderate depression, comparing high-intensity exercise, low-intensity exercise, and social activities.
- Participants were recruited through mental health services and schools, with the intervention delivered over 12 weeks by trained professionals.
- Results showed a 71.4% retention rate and over 67% attendance, although only 14 participants were randomized from the initial referrals, indicating challenges in recruitment.
Background & Aim: Perinatal mental health disorders are common complications of pregnancy and the postpartum period. The value of screening for their early detection is well-recognized, but to-date, research-validated mental health measures for postpartum women in Malta are lacking. In this prospective cross-sectional study, we assessed the validity of the Edinburgh Postnatal Depression Scale (EPDS), an EPDS subscale (EPDS-3A), and the Generalised Anxiety Disorder-7 item (GAD-7) as screening measures for postpartum depression and anxiety.
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