Publications by authors named "K J Gayathri"

Introduction: To evaluate the enamel abrasion effects of soft, ultra-soft, and nano-bristle toothbrushes using atomic force microscopy (AFM) to guide toothbrush selection for optimal enamel preservation.

Methods: This in vitro study involved 45 extracted human teeth (central and lateral incisors), randomly assigned to three groups (n=15 each): Group I (nano-bristle), Group II (ultra-soft bristle), and Group III (soft bristle). Each specimen underwent 10,000 brushing cycles with a standardized 2 N force to simulate one year of brushing.

View Article and Find Full Text PDF

Background: Periodontal disease is a major contributing factor to tooth loss and can significantly impact overall health. Traditional periodontal therapy typically involves mechanical debridement to remove plaque and calculus, along with the use of antimicrobial agents to reduce bacterial load. Licorice () has a long history of use in traditional medicine for treating various ailments since it contains glycyrrhizin, glabridin, liquiritin, and flavonoids, which possess anti-inflammatory, antioxidant, and antimicrobial activities.

View Article and Find Full Text PDF
Article Synopsis
  • Systemic lupus erythematosus (SLE) is an autoimmune disease with varied symptoms, primarily affecting women but often leading to more severe cases in men, necessitating a deeper understanding of gender-specific outcomes for effective management.
  • There is currently no cure for SLE; treatment focuses on managing symptoms and preventing disease flares, while patients face increased risks of infections that complicate management.
  • The review includes a thorough literature search to analyze gender influences on SLE's clinical consequences and outlines the need for research to improve treatment strategies tailored to gender variations.
View Article and Find Full Text PDF

Aim To evaluate the biocompatibility of ethanolic extract of (bael/vilvam) leaves with gingival fibroblast cells.  Materials and methods Commercially available bael leaves were used to produce a herbal ethanolic extract using the cold percolation technique. Evaluation of cytotoxicity of the bael leaf extract (BLE) on fibroblast cell line at six different concentrations (200µl/ml, 100µl/ml, 50µl/ml, 25µl/ml, 12.

View Article and Find Full Text PDF
Article Synopsis
  • - Periodontitis is caused by harmful bacteria, and traditional treatments often rely on mechanical cleaning and chemical agents, which can lead to side effects and antibiotic resistance. Researchers are considering herbal remedies like Tulsi for their effectiveness and fewer adverse effects.
  • - This study investigates the antibacterial power of Tulsi's ethanolic extract against a significant periodontal bacterium, using chlorhexidine, a common treatment, as a comparison.
  • - The results showed that Tulsi's extract was effective, especially at higher concentrations (25 mg/mL produced a 17 mm zone of inhibition, and 50 mg/mL produced a 25 mm), although chlorhexidine still had a greater effect (32 mm zone).
View Article and Find Full Text PDF