Sex-Specific White Matter Abnormalities Across the Dynamic Pain Connectome in Neuropathic Pain: A Fixel-Based Analysis Study.

A fundamental issue in neuroscience is a lack of understanding regarding the relationship between brain function and the white matter architecture that supports it. Individuals with chronic neuropathic pain (NP) exhibit functional abnormalities throughout brain networks collectively termed the "dynamic pain connectome" (DPC), including the default mode network (DMN), salience network, and ascending nociceptive and descending pain modulation systems. These functional abnormalities are often observed in a sex-dependent fashion.

Health Care Utilisation and Unmet Needs in Survivors of Head and Neck Cancer in Regional Australia: A Cross-Sectional Survey.

Background: The post-treatment survivorship period marks the transition away from acute care and poses distinct challenges for individuals with head and neck cancer (HNC). This can be especially challenging for people in regional areas who travel long distances to access care and experience unique challenges in accessing health services.

Aim: To investigate unmet needs and healthcare utilisation of survivors of HNC in regional areas.

Groundwater releases CO to diverse global coastal ecosystems.

Coastal ecosystems play a major role in marine carbon budgets, but substantial uncertainties remain in the sources and fluxes of coastal carbon dioxide (CO). Here, we assess when, where, and how submarine groundwater discharge (SGD) releases CO to shallow coastal ecosystems. Time-series observations of dissolved CO and radon (Rn, a natural groundwater tracer) across 40 coastal systems from 14 countries revealed large SGD-derived CO fluxes.