Publications by authors named "K J Como-Sabetti"
SARS-CoV-2 transmission dynamics within households involving children are complex. We examined the association between paediatric index case (PIC) age and subsequent household SARS-CoV-2 transmission among cases reported to the Minnesota Department of Health between March 2021 and February 2022. In our primary analysis, we used logistic regression to estimate odds ratios adjusted for race/ethnicity, sex, geographic region, and disease severity among households with an unvaccinated PIC.
View Article and Find Full Text PDFImportance: Respiratory syncytial virus (RSV) infection can cause severe illness in adults. However, there is considerable uncertainty in the burden of RSV-associated hospitalizations among adults prior to RSV vaccine introduction.
Objective: To describe the demographic characteristics of adults hospitalized with laboratory-confirmed RSV and to estimate annual rates and numbers of RSV-associated hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths.
Article Synopsis
- * An analysis of 44,816 hospitalizations revealed that 90% of cases were likely attributable to COVID-19, particularly focusing on admissions from July 2022 to September 2023, where 86% were linked to COVID-19-related symptoms and treatments.
- * The research found that younger adults and those without underlying health conditions were less likely to have COVID-19-attributable hospitalizations, suggesting that severe cases are more prevalent in older patients and those with pre-existing health issues.
Article Synopsis
- Minnesota expanded its viral genomic surveillance to include human respiratory syncytial virus (RSV).
- Whole-genome sequencing was performed on 575 specimens collected from healthcare facilities between July 2023 and February 2024.
- Two subgroups of RSV, A and B, showed distinct genomic differences, and researchers identified 23 clusters of genetically identical genomes.
Among adults, COVID-19 hospitalization rates increase with age. Data from the COVID-19-Associated Hospitalization Surveillance Network were analyzed to estimate population-based COVID-19-associated hospitalization rates during October 2023-April 2024 and identify demographic and clinical characteristics of adults aged ≥18 years hospitalized with COVID-19. Adults aged ≥65 years accounted for 70% of all adult COVID-19-associated hospitalizations, and their COVID-19-associated hospitalization rates were higher than those among younger adult age groups.
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