Publications by authors named "K J Choudhury"
Background: Diabetic population are at an increased risk of developing dyslipidemia and other cardiovascular complications. The study was performed to evaluate the lipid profile parameter in the diabetic population among the ethnic tribal community of Tripura and calculate the risk of cardiovascular events. The tribal community was chosen as the study population because their lifestyle, food habits, culture and housing practices are different from people living on the plains.
View Article and Find Full Text PDFIntroduction: Similar presenting manifestations in early phase and lack of awareness of aetiology of acute febrile illness (AFI) are major challenges in management of AFI.
Material And Methods: This was a retrospective observational cross-sectional study conducted in the Department of Microbiology, NRS Medical College, from 1 July 2022 to 30 June 2023 in serologically diagnosed febrile patients attending the outpatient department or admitted. Clinical and epidemiological data and laboratory parameters were recorded in a pretested structured questionnaire study tool, and collected data were analysed on MS-Excel sheets with various charts and tables.
Article Synopsis
- * The study developed doxorubicin-loaded mesoporous silica nanoparticles (DMSNs) from cucumber peels to target lung adenocarcinoma cells, showing effective drug delivery and antibacterial properties against infections common in lung cancer patients.
- * This method not only offers a promising anticancer treatment but also promotes sustainability by turning food waste into useful medical nanoparticles, aligning with the waste-to-health paradigm.
Article Synopsis
- Triple-negative breast cancer (TNBC) is highly aggressive due to a lack of targetable bioreceptors and features like epithelial to mesenchymal transition (EMT), which enhances its metastatic abilities.
- Researchers developed a combination therapy using promethazine hydrochloride-loaded PLGA nanoparticles, which showed efficient delivery and anti-cancer effects in experimental studies, particularly when used alongside the histone deacetylase inhibitor SAHA.
- The study found that SAHA not only increased the effectiveness of the drug-loaded nanoparticles but also altered EMT dynamics, promoting a shift towards less aggressive cancer cell characteristics, thus highlighting the potential of combining nanotechnology with repurposed drugs for treating TNBC.
Dengue fever is a rapidly emerging tropical disease and an important cause of morbidity in its severe form worldwide. A wide spectrum of the pathophysiology is associated with the transition of dengue fever to severe dengue, which is driven by the host immune response and might reflect in patients' proteome profile. This study aims to analyze the plasma from different phases of dengue-infected patients at two time points.
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