Publications by authors named "K J Beer"
Background: Temple hollowing is characterized by the reduction of volume in the temporal fossa, which can result in a skeletonized look and contribute to an aged appearance. This study aimed to evaluate the safety and effectiveness of the VYC-20L injectable gel for improvement of temple hollowing.
Methods: Adults with minimal, moderate, or severe temple hollows were randomized 2:1 to receive VYC-20L or no treatment.
Inclusion body myositis (IBM) is an inflammatory myopathy, characterised by slow progression of weakness, skeletal muscle atrophy, and heterogeneous clinical presentation. This variability in disease progression and presentation complicates tracking of clinical progress and intervention response in clinical trials, presenting challenges in identifying reliable outcome measures. We aimed to identify the most useful suite of clinician-assessed and patient-reported outcome measures (PROMs) for use in clinical practice and trials from a selection of the most commonly used outcome measures in IBM.
View Article and Find Full Text PDFTime memory in social insects with a special focus on honey bees.
Curr Opin Insect Sci
December 2024
The ability to associate time and location with food sources is an evolutionary advantage for foraging animals. We find highly sophisticated time memory capabilities especially in social insects, which require efficient foraging capabilities for colony provisioning. Honey bees are perfectly suitable to study time memory mechanisms: they possess an elaborated time memory combined with a relatively simple neuronal clock network and a smaller gene set compared with the mouse model organism.
View Article and Find Full Text PDFArticle Synopsis
- IIMs are autoimmune diseases that lead to muscle inflammation and have serious health impacts, but due to their rarity and variability, understanding these conditions has been difficult.
- The Australian Myositis Registry (AMR) is a new national database that collects clinical and patient data from IIM patients in Australia to enhance research and improve outcomes.
- Launched in 2023 with 170 participants so far, the AMR aims to expand its reach and is significant as Australia’s first national registry for IIMs, providing crucial data for understanding the diseases' epidemiology and improving patient care.
Background: Validated patient-reported outcome measures to assess disease impact in patients with adult idiopathic inflammatory myopathies (IIMs) are needed. The objective of this study was to assess the construct validity of PROMIS Pain Interference, Fatigue, and Physical Function measures in comparison with core disease activity measures.
Methods: Adults with IIM, excluding inclusion body myositis, from OMERACT Myositis Working Group (MWG) clinic sites completed PROMIS Short Form v1.