Advances in aquatic animal health within the framework of the World Organisation for Animal Health.

The World Organisation for Animal Health (WOAH) seeks to improve animal health by promoting safe trade in animals and their products, setting standards for diagnostic methods, detection of emerging diseases and confirmation of listed diseases in clinically affected animals and surveillance in healthy populations. WOAH launched the Aquatic Animal Health Strategy (AAHS) in 2021 in recognition of the growing importance of aquatic animal products in global food security. Disease is currently a major limiting factor in the sustainable growth and development of the aquaculture industry, impacting the industry's ability to increase yields to meet future food demands.

Environmentally sustainable opportunities for health systems: Metered-dose inhaler prescribing, dispensing, use and waste at a tertiary academic centre.

Background: The Canadian health sector's carbon footprint is among the highest in the world and is responsible for 4.6% of Canada's total greenhouse gas emissions, a quarter of which is linked to pharmaceuticals, with metered-dose inhalers (MDIs) contributing disproportionally high amounts.

Objectives: To describe MDI prescribing, dispensing, use and waste patterns at a Canadian tertiary care academic hospital.

A model of lymphocryptovirus-associated post-transplant lymphoproliferative disorder in immunosuppressed Mauritian cynomolgus macaques.

Immunocompromised individuals are at risk for developing lymphocryptovirus-associated lymphoproliferative diseases, such as Epstein Barr virus (EBV)-associated B cell lymphomas and post-transplant lymphoproliferative disorder (PTLD). We previously reported development of cynomolgus lymphocryptovirus (CyLCV)-associated PTLD in Mauritian cynomolgus macaques (MCMs) undergoing hematopoietic stem cell transplantation (HSCT), which mirrored EBV-PTLD in transplant patients. Here, we sought to develop a MCM model of lymphocryptovirus-associated lymphoproliferative disease in immunosuppressed MCMs without HSCT.

Identification of Albopleistophora grylli n. gen. n. sp. (Microsporidia) and its impact on crickets (Gryllus spp.) in food-and-feed culture systems.

This study provides a comprehensive taxonomic description of a microsporidian parasite infecting crickets, Gryllus bimaculatus and G. assimilis. Our analysis includes gross pathology, histopathology, spore ultrastructure, parasite development cycle, single gene phylogenies, and phylogenomic comparisons.

Acute estradiol and progesterone therapy in hospitalized adults to reduce COVID-19 severity: a randomized control trial.

COVID-19 outcomes are less severe in women than men suggesting that female sex is protective. The steroids estradiol (E2) and progesterone (P4) promote anti-inflammatory immune responses and their therapeutic use for COVID-19 has been under investigation. The aim of the study was to evaluate the efficacy of a short systemic E2 and P4 combination in mitigating COVID-19 severity in hospitalized men and women.