Publications by authors named "K Isaac-Olive"

This paper presents a new method for correcting the contribution of scattered radiation to the measurement of 99mTc internal activity in nuclear medicine patients using gamma cameras. So, this study aims to derive scattering correction factors by Monte Carlo simulation for anterior and posterior count rates (${I}_{\mathrm{A}}$ and ${I}_{\mathrm{P}}$) in the conjugate view method, enabling more precise estimation of activity A(t) compared to traditional trapezoidal and triangular approximations. The new approach eliminates the need to use photopeak for determining the fraction of scattered photons.

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Drug delivery through the skin is a widely used therapeutic method for the treatment of local dermatologic conditions. Dermal and transdermal methods of drug delivery offer numerous advantages, but some of the most important aspects of drug absorption through the skin need to be considered. Film-forming systems (FFS) represent a new mode of sustained drug delivery that can be used to replace traditional topical formulations such as creams, ointments, pastes, or patches.

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Background Aims: Gene-silencing by small interfering RNA (siRNA) is an attractive therapy to regulate cancer death, tumor recurrence or metastasis. Because siRNAs are easily degraded, it is necessary to develop transport and delivery systems to achieve efficient tumor targeting. Self-nanoemulsifying systems (SNEDDS) have been successfully used for pDNA transport and delivery, so they may be useful for siRNA.

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. The currently available dosimetry techniques in computed tomography can be inaccurate which overestimate the absorbed dose. Therefore, we aimed to provide an automated and fast methodology to more accurately calculate the SSDE usingDwobtained by using CNN from thorax and abdominal CT study images.

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