Prevalence of pulmonary hypertension in an unselected, mixed connective tissue disease cohort: results of a nationwide, Norwegian cross-sectional multicentre study and review of current literature.

Objectives: The aim of this study was to assess the overall prevalence of pulmonary hypertension (PH) in an unselected MCTD cohort and review the current knowledge with a systematic database search.

Methods: A nationwide multicentre cohort of 147 adult MCTD patients were initially screened for PH by echocardiography, high-resolution computed tomography (HRCT), pulmonary function tests and N-terminal pro-brain natriuretic peptide (NT-proBNP) and then followed up for a mean of 5.6 years.

Prevalence and severity of interstitial lung disease in mixed connective tissue disease: a nationwide, cross-sectional study.

Background: Mixed connective tissue disease (MCTD) is an immune-mediated, systemic disorder of unknown cause.

Objective: To assess the prevalence, pattern and severity of interstitial lung disease (ILD) in a cross-sectional study of the nationwide, Norwegian MCTD cohort.

Methods: 126 patients with MCTD were systematically examined for ILD by high-resolution CT (HRCT), pulmonary function tests (PFT), 6 min walk test (6MWT) and by the New York Heart Association (NYHA) functional classification of dyspnoea.

[Scalp necrosis in temporal arteritis].

Background: Temporal arteritis is a systemic granulomatous vasculitis affecting large and medium sized arteries. Scalp necrosis is a rare complication that can appear before, during and after treatment.

Material And Methods: A patient with temporal arteritis and scalp necrosis is presented and relevant literature reviewed.

[Experimental paratuberculosis: pathogenicity of mycobactin-dependent mycobacteria strains to calves].

The pathogenicity for calves of two strains of wood-pigeon mycobacteria isolated in our laboratory, one strain isolated in the United Kingdom, one strain isolated from a Roe-deer in Denmark and three strains of M. paratuberculosis, were compared. Seven groups of four 3 to 4 week-old calves were infected by the intravenous route using 10(6) to 10(9) viable units.