Publications by authors named "K Iqbal"
Extreme-cum-median ranked set sampling has been developed to address the problem of heterogeneity and outliers / extreme values. Double ranked set sampling has been suggested to obtain more reliable samples using the concept of degree of distinguishability. Dealing with heterogeneous and non-normal populations seems to be an area with a dearth of research.
View Article and Find Full Text PDFFirefighters need personal protection equipment and protective clothing to be safe and protected when responding to fire incidents. At present, firefighters' suits are developed by using inherently thermal-resistant fibers but pose serious problems related to comfort. In the present research, multilayered fire-fighting fabrics were developed with different fiber blends.
View Article and Find Full Text PDFBackground: Central serous chorioretinopathy (CSC) is a significant cause of vision loss in men aged 20 to 60, characterized by serous detachment of the neurosensory retina from the retinal pigment epithelium (RPE). This study aims to assess the frequency of CSC among patients at a tertiary care center in Pakistan, offering insights into its epidemiology and management within this setting.
Methodology: A retrospective observational study was conducted at the ophthalmology department of a tertiary care center from January 2019 to December 2023.
Background: A wide variety of vitreoretinal diseases have been majorly treated by the use of pars plana vitrectomy (PPV) as the most commonly practiced treatment option. Despite the fact that it is the most feasible treatment modality, the probability of corneal endothelial cell damage following the treatment remains a matter of great concern. The study aims to inquire about the aftermath of PPV on endothelial cell density (ECD) and spans a time period of six months after the surgery has been performed.
View Article and Find Full Text PDFArticle Synopsis
- TFAP2C is a crucial transcription factor in the development of trophoblast cells and hemochorial placentation, particularly in rats, which have a placentation process similar to humans.
- Research using genome editing showed that completely removing TFAP2C led to prenatal death, while reducing its levels resulted in less invasion of trophoblast cells into the uterus.
- Conditional mutagenesis revealed that targeted disruption of TFAP2C in invasive trophoblast cells hindered their invasion capacity and affected growth, indicating its important role in both early and later stages of placental development.