Publications by authors named "K Imaeda"

Article Synopsis
  • * This study focused on Au nanoblocks with varying Al2O3 layer thicknesses to explore how these layers affect acoustic phonon frequencies.
  • * Results showed that higher Al2O3 thickness leads to increased acoustic phonon frequencies, suggesting that changes in density are the main reason for this frequency modulation, helping to advance mass sensing technology.
View Article and Find Full Text PDF

Soft-crystals are defined as flexible molecular solids with highly ordered structures and have attracted attention in molecular sensing materials based on external triggers and environments. Here, we show the soft-crystal copolymerization of green-luminescent Tb(III) and yellow-luminescent Dy(III) coordination centers. Soft-crystal polymerization is achieved via transformation of monomeric dinuclear complexes and polymeric structures with respect to coordination number and geometry.

View Article and Find Full Text PDF

To improve the efficacy and safety of chimeric antigen receptor (CAR)-expressing T cell therapeutics through enhanced CAR design, we analysed CAR structural factors that affect CAR-T cell function. We studied the effects of disulphide bonding at cysteine residues and glycosylation in the HD on CAR-T function. We used first-generation CAR[V/28/28/3z] and CAR[V/8a/8a/3z], consisting of a mouse vascular endothelial growth factor receptor 2 (VEGFR2)-specific single-chain variable fragment tandemly linked to CD28- or CD8α-derived HD, transmembrane domain (TMD) and a CD3ζ-derived signal transduction domain (STD).

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the relationship between gastric motility and upper gastrointestinal symptoms in patients with long-standing diabetes mellitus (DM), who often report issues like appetite loss and abdominal pain.
  • Researchers compared 23 DM patients (with complications like nephropathy or neuropathy) to 15 healthy individuals, using electrogastrography and breath tests to evaluate gastric function.
  • Results indicated that DM patients had significantly delayed gastric emptying and abnormalities in gastric activity, with a notable correlation between these dysmotility issues and the presence of GI symptoms.
View Article and Find Full Text PDF

The geometrical shape of a metal nanostructure plays an essential role in determining the optical functionality of plasmonic cavity modes. Here, we investigate the geometrical modification effect on plasmonic cavity modes induced in two-dimensional gold nanoplates. We perform near-field transmission measurements on triangular and tip-truncated triangular nanoplates and reveal that the plasmonic cavity modes are qualitatively consistent with each other as long as the snipping size is not significant.

View Article and Find Full Text PDF