Effect of mitomycin C dissolved in reversible thermo-setting gel on the outcome of filtering surgery in the rabbit.

Purpose: Based on our previous report that showed enhanced transfer of mitomycin C to the sclera and the conjunctiva by dissolving the agent into a reversible thermo-setting gel, we conducted a study to investigate the efficacy of mitomycin C gel in the rabbit.

Methods: We subconjunctivally injected 0.1 mL of the mitomycin C gel solution containing several different amounts of the agent.

[Effect of mitomycin C dissolved in a reversible thermosetting gel on outcome of filtering surgery in the rabbit].

Purpose: Based on our previous report that showed enhanced transfer of mitomycin C to the sclera and the conjunctiva by dissolving the antiproliferative in a reversible thermo-setting gel, we conducted a study to investigate the efficacy of the mitomycin C-gel in the rabbit.

Methods: We subconjunctivally injected 0.1 ml of the mitomycin C-gel solution containing several amounts of the drug.

Mitomycin C dissolved in a reversible thermosetting gel: target tissue concentrations in the rabbit eye.

Aims: To determine whether a new, reversible thermosetting gel enhances mitomycin C transfer to target ocular tissues in the rabbit eye.

Methods: A 0.1 ml solution of mitomycin C containing 0.

Prevention of visual field defect progression with brovincamine in eyes with normal-tension glaucoma.

Purpose: A prospective investigation of the effect of brovincamine fumarate, a Ca2+-channel blocker, on visual field changes in normal-tension glaucoma (NTG).

Methods: A total of 28, age- and field-matched, patients with NTG were allocated randomly to either brovincamine fumarate (20 mg 3 times daily) or placebo (3 times daily). The patients were followed at least every 4 months for a minimum of 2.