Continuous-wave optically stimulated luminescence properties of Guajillo chilli polyminerals exposed to gamma radiation.

In this investigation, the Continuous-Wave Optically Stimulated Luminescence (CW-OSL) properties of polyminerals extracted from Mexican and Peruvian Guajillo chilli were studied using a source of cesium-137 (Cs-137) gamma radiation. The Guajillo chilli polyminerals were stimulated with blue light for 120 s, and their luminescence was detected in the UV region. The General Order Kinetics (GOK) deconvolution analysis of the CW-OSL curves was carried out using three individual components.

Adsorption and Activation of CO on Nitride MXenes: Composition, Temperature, and Pressure effects.

The interaction of CO with nitride MXenes of different thickness is investigated using periodic density functional theory-based calculations and kinetic simulations carried out in the framework of transition state theory, the ultimate goal being predicting their possible use in Carbon Capture and Storage (CCS). We consider the basal (0001) surface plane of nitride MXenes with M N (n=1-3; M=Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, and W) stoichiometry and also compare to equivalent results for extended (001) and (111) surfaces of the bulk rock-salt transition metal nitride compounds. The present results show that the composition of MXenes has a marked influence on the CO -philicity of these substrates, whereas the thickness effect is, in general, small, but not negligible.

Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.

Unlabelled: The four dengue virus (DENV) serotypes, DENV1 through 4, are endemic throughout tropical and subtropical regions of the world. While first infection confers long-term protective immunity against viruses of the infecting serotype, a second infection with virus of a different serotype carries a greater risk of severe dengue disease, including dengue hemorrhagic fever and dengue shock syndrome. Recent studies demonstrate that humans exposed to DENV infections develop neutralizing antibodies that bind to quaternary epitopes formed by the viral envelope (E) protein dimers or higher-order assemblies required for the formation of the icosahedral viral envelope.

DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers.

There are four closely-related dengue virus (DENV) serotypes. Infection with one serotype generates antibodies that may cross-react and enhance infection with other serotypes in a secondary infection. We demonstrated that DENV serotype 2 (DENV2)-specific human monoclonal antibody (HMAb) 2D22 is therapeutic in a mouse model of antibody-enhanced severe dengue disease.