Publications by authors named "K I Nibu"
Bilateral congenital cholesteatoma (BCC) is rare among congenital cholesteatoma (CC) cases, and bilateral surgery poses a significant psychophysical burden on pediatric patients. Here, we present 2 pediatric cases of BCC that were successfully managed using simultaneous bilateral transcanal endoscopic ear surgery (TEES). The surgical approach provided clear visualization of the middle ear structures, enabling successful cholesteatoma removal with minimal invasiveness and a short operative time.
View Article and Find Full Text PDFObjective: After a total laryngectomy, patients lose various physiological functions of the upper airway. To address these issues, an artificial nose (heat and moisture exchanger (HME)) has been developed. However, the current HMEs do not provide sufficient physiological upper airway function.
View Article and Find Full Text PDFArticle Synopsis
- Surgical excision of advanced lacrimal gland carcinoma often requires removing the orbital contents and reconstructing the anterior skull base with tissue that can withstand radiotherapy; this process involves complex considerations regarding patient quality of life and aesthetics.
- In three cases, a rectus abdominis flap was utilized for reconstruction after en bloc resection, chosen for its reliable structure and blood flow to fill the surgical cavity.
- The flap successfully survived with no complications, but showed notable shrinkage after six months, leading to the recommendation for using a slightly larger flap volume initially to account for future reductions.
Aim: Although immune checkpoint inhibitors (ICPi) for salivary gland cancer (SGC) have been investigated in clinical trials, details of the tumor immune microenvironment (TIME) remain unclear. This research aimed to elucidate the TIME of SGC and its relationship with tumor mutation burden (TMB) and to explore the rationale for the applicability of ICPi.
Materials And Methods: We selected five pathological types, namely adenoid cystic carcinoma (ACC); adenocarcinoma, not otherwise specified (ANOS); salivary duct carcinoma (SDC); and low/high-grade mucoepidermoid carcinoma (MEC).