Publications by authors named "K Holmes"

The accuracy of using HEART (history, electrocardiogram, age, risk factors, and troponin) scores with high-sensitivity cardiac troponin (hs-cTn) to risk stratify emergency department (ED) chest pain patients remains uncertain. We aim to compare the performance accuracy of determining major adverse cardiac event (MACE) among three modified HEART (mHEART) scores with the use of hs-cTn to risk stratify ED chest pain patients. This retrospective single-center observational study included ED patients with suspected acute coronary syndrome who had HEAR scores calculated and at least one hs-cTnI result.

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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were originally developed for the treatment of type 2 diabetes but have recently been approved for chronic weight management and reducing cardiovascular risk in individuals with overweight and obesity. Despite this approval, significant heterogeneity in the cardioprotective benefits and less desirable increases in resting heart rate (RHR) with GLP-1 RAs have been reported. To better understand cardiovascular responses to GLP-1 RAs, and the potential role of health behaviors in influencing these responses, we leveraged wearable technology and causal inference analysis.

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When we use language to communicate, we must choose what to say, what not to say, and how to say it. That is, we must decide how to the message. These linguistic choices matter: Framing a discussion one way or another can influence how people think, feel, and act in many important domains, including politics, health, business, journalism, law, and even conversations with loved ones.

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Article Synopsis
  • Many U.S. states improved Medicaid coverage for tobacco dependence treatment (TDT) in the last fifteen years, but its effects on smoking behaviors, particularly for individuals with substance use disorders (SUD), are unclear.
  • A study using data from the National Survey on Drug Use and Health (2009-2018) examined the smoking habits of Medicaid beneficiaries aged 18-64 with SUD, finding that the expansion of TDT coverage did not significantly impact smoking cessation or nicotine dependence.
  • The research concluded that comprehensive TDT coverage did not lead to changes in smoking behaviors among Medicaid beneficiaries with SUD, suggesting that additional interventions may be required to effectively address smoking among this population.
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Article Synopsis
  • The study aimed to assess the acceptability and feasibility of the Screening and Support for Youth (SASY), a community-based program that provides mental health screening and support for diverse youth.
  • Using various tools, the SASY screening evaluated symptoms, functioning, and clinical risks, leading to personalized insights for participants during motivational interviews and options for online interventions.
  • Innovative recruitment methods, enhanced by the pandemic (like using QR codes), successfully increased participation, particularly among Black or African American and Hispanic youth, showing that combining online and offline strategies can effectively engage a diverse population.
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