Publications by authors named "K Holmberg"

Studies addressing patients' experiences of person-centered care (PCC) in the context of allogeneic hematopoietic stem cell transplantation (allo-HSCT) are scarce; hence, this study aimed to explore patients' experiences of PCC, and its associations with individual characteristics and health-related quality of life, in the context of allogeneic stem cell transplantation. It is a cross-sectional survey study, in patients who had undergone an allo-HSCT at one center in Sweden. The PCC instrument for outpatient care in rheumatology (PCCoc/rheum) was used.

View Article and Find Full Text PDF

Background Context: Cervical Disc Arthroplasty (CDA) has been shown to be an effective and safe alternative to Anterior Cervical Discectomy and Fusion (ACDF), with randomized controlled trials (RCTs) reporting non-inferior or even favorable outcomes to ACDF. However, the current literature of large RCTs reporting long-term outcomes of CDA primarily comprises of the industry sponsored Food and Drug Administration (FDA) Investigational Device Exemption (IDE) trials. As a result, CDA has yet to be universally accepted by surgeons due to concerns of bias in the current literature.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers discovered a new compound called sanyensin from deep-sea bacteria, characterized by its unique macrodiolide structure.
  • They established its stereochemistry using advanced techniques like NOEs and a novel workflow that simplifies the analysis of flexible molecular structures.
  • This study enhances understanding of deep-sea microbial biosynthesis and offers a streamlined approach for identifying and confirming new natural products.
View Article and Find Full Text PDF

The global corrosion cost is estimated to be around 2.5 trillion USD, which is more than 3 % of the global GDP. Against this background, large efforts have been made to find effective corrosion inhibitors.

View Article and Find Full Text PDF
Article Synopsis
  • Clinical trials indicate that cervical disc arthroplasty (CDA) is a safe, effective alternative to anterior cervical discectomy and fusion (ACDF) for treating cervical degenerative disc disease, with various CDA devices available that differ in constraint levels.
  • The study utilized a systematic review and network meta-analysis comparing outcomes of ACDF versus CDA across different constraint levels in a sizable patient sample over at least two years.
  • Results showed that both semiconstrained and unconstrained CDA types had a lower risk of adjacent segment degeneration and subsequent surgeries compared to ACDF; semiconstrained CDA also had a lower risk of reoperation at the index level.
View Article and Find Full Text PDF