Publications by authors named "K Hoch"

Treatment with antibiotics is a major risk factor for infection, likely due to depletion of the gastrointestinal microbiota. Two microbiota-mediated mechanisms thought to limit colonization include the conversion of conjugated primary bile salts into secondary bile salts toxic to growth and competition between the microbiota and for limiting nutrients. Using a continuous flow model that simulates the nutrient conditions of the distal colon, we investigated how treatment with 6 clinically used antibiotics influenced susceptibility to infection in 12 different microbial communities cultivated from healthy individuals.

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Objective: Evaluate the risk factors for the development of post-molar gestational trophoblastic neoplasia.

Methods: Retrospective cohort study with 320 women with gestational trophoblastic disease (GTD) followed in a tertiary hospital from January 2005 to January 2020. Data referring to the women's sociodemographic profile, clinical, laboratory and treatment aspects and types of GTD were analyzed.

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Article Synopsis
  • Taking antibiotics can mess up the healthy bacteria in our gut, which might make it easier for infections to happen.
  • The study looked at how different antibiotics changed the bacteria in healthy people's intestines and found that different antibiotics affected them in different ways.
  • Surprisingly, some changes in bacteria and bile salts didn’t necessarily mean a higher chance of infection, showing there are other ways bacteria can control infections without relying just on bile salts.
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Histamine is an important biogenic amine known to impact a variety of patho-physiological processes ranging from allergic reactions, gut-mediated anti-inflammatory responses, and neurotransmitter activity. Histamine is found both endogenously within specialized host cells and exogenously in microbes. Exogenous histamine is produced through the decarboxylation of the amino acid L-histidine by bacterial-derived histidine decarboxylase enzymes.

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Unlabelled: We created high-resolution shape models of Phobos and Deimos using stereophotoclinometry and united images from Viking Orbiter, Phobos 2, Mars Global Surveyor, Mars Express, and Mars Reconnaissance Orbiter into a single coregistered collection. The best-fit ellipsoid to the Phobos model has radii of (12.95 ± 0.

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