Publications by authors named "K Hirota"

Background: Hypermagnesemia is a rare complication, leading to fatal cardiovascular and respiratory conditions. We present severe hypermagnesemia developed in a patient with a rectal stenosis after pretreatment with oral magnesium citrate for rectosigmoid surgery.

Case Presentation: A 78-year-old woman demonstrated consciousness disturbance, muscle weakness, and respiratory depression requiring tracheal intubation after preparation with oral magnesium for rectosigmoid surgery.

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Article Synopsis
  • Proper glycemic control is important in critical care settings, as it can impact patient outcomes and is influenced by factors such as insulin secretion and glucose metabolism.
  • Various perioperative drugs, particularly dexmedetomidine (DEX), are shown to suppress glucose-stimulated insulin secretion, but the mechanisms remain unclear.
  • Research using pancreatic cell lines and primary cells indicates that DEX reduces insulin secretion without significantly altering other cellular processes, suggesting that it affects insulin signaling pathways and exocytosis mechanisms.
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Rationale: Mirror syndrome is a rare pregnancy condition in which maternal edema is associated with fetal hydrops. Because of its rarity and overlapping symptoms, this condition is often misdiagnosed as another pregnancy complication.

Patient Concerns: A 28-year-old pregnant Japanese woman presented with sudden 7.

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Uric acid (UA) is a final product of purine metabolism and has neuroprotective effects. It has not been established whether serum UA levels are associated with depressive disorder. Thus, we investigated whether serum UA levels are associated with depressive symptoms in a Japanese general population.

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