Publications by authors named "K Hirohata"

Adeno-associated virus (AAV) vectors have attracted significant attention as the main platform for gene therapy. To ensure the safety and efficacy of AAV vectors when used as gene therapy drugs, it is essential to assess their critical quality attributes (CQAs). These CQAs include the genome packaging status, the size of the genome encapsidated within the AAV capsid, and the stoichiometry of viral proteins (VPs) that constitute the AAV capsids.

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Article Synopsis
  • After anterior cruciate ligament reconstruction (ACLR), this study investigates how vertical jump performance relates to athletes' ability to return to their pre-injury competitive level.
  • The study recruited participants who had ACLR using hamstring tendon autografts and evaluated various knee health metrics and jump performance.
  • Findings indicated that those who returned to sport had better vertical jump performance and lower knee pain, suggesting performance symmetry may be crucial for successful RTS.*
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Purpose: We previously reported that a Hammerobics exercise using weights can enhance trunk and lower extremity muscles, some studies suggested that training effects could also be expected without heavy weights. If the muscle activity induced by Hammerobics swinging with a 'light plastic ball' equals or surpasses that of the isometric static squat and synchronized squat with a heavy ball, this training approach could alleviate joint strain, fostering an exercise regimen universally accessible across generations, benefit for workouts sports and rehabilitation.

Methods: Fifteen healthy men participated in this study.

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  • The KOJI AWARENESS (KA) test evaluates movement function and could help create personalized training plans, but its ability to predict injuries in runners was unexamined.
  • A study involving 47 elite college male long-distance runners found that those with injuries had significantly lower KA scores during preseason assessments.
  • The research indicated that a KA score below 46.5 points could predict running-related injuries with a sensitivity of 73% and specificity of 63.6%, suggesting it's a valuable tool for injury prevention in this athlete group.
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The KOJI AWARENESS (KA) screening test assesses motor function in humans. We aimed to analyze the correlation between age and KA screening scores and to identify the specific age at which a significant decline occurs. A total of 793 healthy participants (234 females) were interviewed for basic information on age and sex and completed the KA screening test.

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