Publications by authors named "K Hebbrecht"
Article Synopsis
- Depression is typically viewed as a disease caused by a common factor, but this study takes a network approach, focusing on how individual symptoms influence each other and their dynamics over time.
- Using the Symptom Questionnaire-48 (SQ-48), researchers examined patient data with dynamic time warp analyses, discovering significant interconnections between various symptoms and how certain symptoms led to changes in others.
- The study identified five symptoms ('hopeless', 'restless', 'down/depressed', 'feeling tense', and 'no enjoyment') that could be targeted for more effective, personalized treatments, though the focus on severely depressed inpatients limits the generalizability of the findings.
The Global ECT MRI Research Collaboration (GEMRIC) has collected clinical and neuroimaging data of patients treated with electroconvulsive therapy (ECT) from around the world. Results to date have focused on neuroimaging correlates of antidepressant response. GEMRIC sites have also collected longitudinal cognitive data.
View Article and Find Full Text PDFBackground: While theta burst stimulation (TBS) shows promise in Major Depressive Disorder (MDD), its effectiveness in bipolar depression (BD-D) remains uncertain. Optimizing treatment parameters is crucial in the pursuit of rapid symptom relief. Moreover, aligning with personalized treatment strategies and increased interest in immunopsychiatry, biomarker-based stratification of patients most likely to benefit from TBS might improve remission rates.
View Article and Find Full Text PDFIntroduction: Electroconvulsive therapy (ECT) related anxiety (ERA) is a common phenomenon with high individual variability. The way patients cognitively cope with the prospects of receiving ECT could be a mechanism explaining individual differences in ERA. Cognitive coping like monitoring (information seeking, paying attention to consequences) and blunting (seeking distraction and reassurance) has been linked to anxiety in various medical settings, with monitoring leading to more and blunting to less anxiety.
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