[Non-invasive assessment of the efficacy of long-term vasodilator therapy of cardiac decompensation in patients with dilated cardiomyopathy].

In 18 patients (14 men, 4 women, in the age of 37-52 years, mean = 43 years) with dilated cardiomyopathy allocated into NYHA functional classification groups III-IV, the efficacy of ambulatory long term (mean = 6 years) vasodilator therapy by means of non-invasive methods was evaluated. NITRO-MACK retard (venodilator) in the dosage of 20 mg per day and DIHYDRALAZIN (arteriodilator) in the dosage of 100-200 mg per day were combined simultaneously with continuous administration of cardiotonics and diuretics. Vasodilator therapy had a favourable effect on systolic and diastolic function of the left ventricle with the mostly marked effect at the beginning of treatment.

[Indications for cardiac surgery on the basis of noninvasive examination methods with major emphasis on echocardiography].

Over the years 1983-1988 cardiosurgical procedures with extracorporeal circulation without catheterization of the heart were indicated in 191 patients, representing 19.8% of all the patients operated on at extracorporeal circulation (n--962). Indications for surgery were made on the basis of the clinical state of the patient and of the results of noninvasive methods, with main emphasis on echocardiographic findings.

[Vectorcardiographic and chronotopocardiographic study of septal hypoperfusion].

The study has been carried out in 73 patients (63 men and 10 women), aged between 22 and 59 years, suffering from angina pectoris. The localization in space of the extremities of the initial QRS vectors (10 and 20 ms) is an indicator which is relatively very sensitive to the disturbance in the myocardial irrigation in the regions around the septum and the adjacent ventricular wall. A good relationship has been found namely with the data obtained with thallium scintigraphy after effort.

[Comparison of echocardiography, vectorcardiography, electrocardiography, coronarography and ventriculography in coronary heart disease].

Fifty patients (9 women, 41 men) with angina pectoris, aged from 22 to 59 years, were examined by means of one- and two-dimensional echocardiography (ECHO), vectorcardiography (VCG) using the McFee-Parungao system of leads, standard 12 lead electrocardiography (ECG), coronarography (CAG), and ventriculography (VG). I of isolated positivity of either of these methods ans considererl as patse positivity and presence or absence of positivity in combination of at least two methods (ECG exeluted) astme positivity, or true negativity then VCG was found to have the highest sensitivity (96%), negative predictive value (80%), as well as the highest overall predictivity (83%), while ECHO had the lowest values, i.e.