Publications by authors named "K Havenga"
Introduction: Anastomotic leakage is a major concern following total mesorectal excision for rectal cancer, affecting oncological outcomes, morbidity an treatment costs. Body composition has been suggested to influence anastomotic leakage rates. However, literature on how body composition impact anastomotic leakage rates is conflicting.
View Article and Find Full Text PDFArticle Synopsis
- In the Netherlands, the use of neoadjuvant radiotherapy for rectal cancer decreased significantly from 2011 to 2016 following a guideline revision, raising concerns about the treatment of locally recurrent rectal cancer (LRRC).
- A study compared two national cohorts from 2011 and 2016, analyzing outcomes such as time to LRRC, metastasis presence, treatment intent, and survival rates.
- Despite the decline in neoadjuvant treatment, the rates of LRRC remained similar, but patients in 2016 had a greater chance of receiving curative treatments and showed improved two-year survival rates after developing LRRC.
Objectives: Minimally invasive total mesorectal excision is increasingly being used as an alternative to open surgery in the treatment of patients with rectal cancer. This systematic review aimed to compare the total, operative and hospitalization costs of open, laparoscopic, robot-assisted and transanal total mesorectal excision.
Methods: This systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) (S1 File) A literature review was conducted (end-of-search date: January 1, 2023) and quality assessment performed using the Consensus Health Economic Criteria.
The gut microbiome has coevolved with its hosts over the years, forming a complex and symbiotic relationship. It is formed by what we do, what we eat, where we live, and with whom we live. The microbiome is known to influence our health by training our immune system and providing nutrients for the human body.
View Article and Find Full Text PDF