Efficacy of microdebrider intracapsular adenotonsillectomy as validated by polysomnography.

Objectives/hypothesis: To evaluate the efficacy of microdebrider intracapsular tonsillectomy (MT) as a treatment for pediatric obstructive sleep apnea (OSA) and sleep disordered breathing.

Study Design: A retrospective study evaluating polysomnogram outcomes for 26 patients who had undergone MT by a sole surgeon (M.G.

Immunoglobulin for concurrent Guillain-Barré and immune thrombocytopenic purpura.

Guillain-Barré syndrome, or acute inflammatory demyelinating polyradiculoneuropathy, and immune thrombocytopenic purpura are both autoimmune disorders thought to result from molecular mimicry in response to an antecedent introduction of foreign antigen. Guillain-Barré syndrome is an ascending motor paralysis that can lead to respiratory compromise. Immune thrombocytopenic purpura is an isolated disorder of platelet destruction leading to mucocutaneous bleeding.

Phase-dependent treatment of delayed sleep phase syndrome with melatonin.

Study Objective: Delayed sleep phase syndrome (DSPS) is a circadian-rhythm sleep disorder characterized by abnormally late sleep and wake times. Melatonin, taken in the evening, advances sleep and circadian phase in patients with DSPS. However, little is known about the most effective dose or time of administration.

Endogenous activation of dopamine D2 receptors regulates dopamine release in the fish retina.

In the fish retina, horizontal cell electrical coupling and light responsiveness is regulated by activation of dopamine D1 receptors that are located on the horizontal cells themselves. The effects of dopamine and dopamine D2 receptor agonists and antagonists on cone horizontal cell light responses were studied in in vitro superfused goldfish retinas. Horizontal cell light responses and electrical coupling were assessed by monitoring responses to full-field stimuli and to small, centered (0.