Evaluation and Management of Thyrotoxicosis During Pregnancy.

This review summarizes the diagnosis and management of thyrotoxicosis in pregnancy. The diagnostic clinical and biochemical considerations used to distinguish the various etiologies of hyperthyroidism from appropriate physiologic changes during pregnancy will be outlined. Finally, the review will discuss the risks and benefits of available options for the treatment of thyrotoxicosis during pregnancy, to mitigate the risks of fetal hyperthyroidism.

Isolation of a novel quercetin derivative from and RT-PCR-assisted probing to investigate its DNA repair in hepatoma cells.

Background And Purpose: DNA damage can lead to carcinogenesis if replication proceeds without proper repair. This study focused on the purification of a novel quercetin derivative present in fruit and studied its protective role in hepatoma cells due to HO-DNA damage.

Experimental Approach: The pure compound obtained from the silica gel column was subjected to structural characterization using spectroscopic techniques.

Changes in glycemic control and body weight over the course of the COVID 19 pandemic in an outpatient setting.

Objective: The COVID-19 pandemic altered health outcomes in populations through a host of downstream social, economic, and psychological changes, especially among those with chronic non-communicable diseases (NCDs). Some studies reveal worsened glycemic control and weight gain, while others indicate improved glycemic control and weight loss. Thus, evidence demonstrates conflicting results in this context.