Publications by authors named "K Haneda"

Article Synopsis
  • There is a growing concern about developmental delays in not just very low birth weight and late preterm infants, but also in early term infants (37-38 weeks) in Japan, where research on this issue is limited.
  • A study utilizing data from the Japan Environment and Children's Study analyzed 104,065 fetal records to assess neurodevelopmental risk in infants at 6 and 12 months old using established questionnaires.
  • Results indicated that early term infants (37-38 weeks) showed significantly higher rates of developmental delays compared to full-term infants (40 weeks), although the risk decreased by the time they reached 12 months.
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A female patient in her 50s who underwent chemotherapy for left primary breast cancer presented with cancerous pleurisy and disseminated intravascular coagulation. Esophagogastroduodenoscopy and liver biopsy revealed gastric and liver cancer. Distinguishing between primary and metastatic cancer by pathological findings is difficult using hematoxylin and eosin staining.

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Membrane vesicles (MVs) are small spherical structures (20-400 nm) produced by most bacteria and have important biological functions including toxin delivery, signal transfer, biofilm formation, and immunomodulation of the host. Although MV formation is enhanced in biofilms of a wide range of bacterial species, the underlying mechanisms are not fully understood. An opportunistic pathogen, , causes chronic infections that can be difficult to treat due to biofilm formation.

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Background: Breast milk, nature's optimum source of nutrition for infants, can contain undesirable microorganisms that cause severe morbidity. After an outbreak of multidrug-resistant Escherichia coli among neonates receiving breast milk donated by another mother in our neonatal intensive care unit (NICU), we were motivated to develop a high-grade breast milk pasteurizer (BMP) designed to thaw and pasteurize breast milk at 63°C for 30 min in a sealed bag without having to open the bag or immerse it in water.

Methods: Pre-existing bacteria and spiked cytomegalovirus (CMV) were measured pre- and post-pasteurization in frozen breast milk donated by mothers of children admitted to the NICU.

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