Publications by authors named "K Hamanaka"
Aim: While considerable data on the alcohol drinking behavior of the general population are available for the United States and Europe, data from Asian countries are scarce. We attempted to estimate the social backgrounds and other factors associated with high Alcohol Use Disorders Identification Test (AUDIT) scores in Japan.
Methods: This web-based survey was conducted in 2023.
Background: While the relationship between gut microbiota and gastrointestinal cancer has been elucidated, the relationship between lung microbiota and lung cancer remains unclear. Previous study findings are inconclusive due to the possibility of contamination by upper airway microbiota in samples obtained from the oropharynx, such as saliva and sputum, and bronchoalveolar lavage fluid (BALF) collected during bronchoscopy. Therefore, this study aimed to detect pure lung microbiota in patients with lung cancer using BALF samples from resected lung specimens.
View Article and Find Full Text PDFBackground: Heterozygous variants of sequestosome-1 gene (SQSTM1) have been reported in patients with various neurological disorders, whereas biallelic pathogenic variants of SQSTM1 can cause child-onset and multisystem neurodegeneration, including cerebellar ataxia, dystonia, and vertical gaze palsy (NADGP). Here, we describe two cases of NADGP in a Japanese family.
Methods: We performed clinical and genetic laboratory evaluations of the two patients and their healthy parents.
Objective: We investigated and compared the long-term (6-month) histologic changes in a rat model of sublobar resection created using electrocautery or stapler techniques.
Methods: Nine-week-old male rats were anesthetized and intubated; thoracotomy with sublobar resection was performed in the right middle lobe using electrocautery or stapler techniques. Histological examination was performed at 2, 4, 8, 12, and 24 weeks post-surgery to assess long-term effects on lung tissue repair and morphologic changes.
Article Synopsis
- Pulmonary segmentectomy for small lung tumors is difficult due to the challenge of achieving sufficient surgical margins, especially when the tumors are near incomplete interlobar fissures.
- RFID marking systems have shown to be helpful in locating small tumors during surgery, allowing for better surgical precision.
- The use of RFID technology in two case studies resulted in successful segmentectomies with adequate margins while conserving lung tissue, demonstrating the method's effectiveness and safety.