Publications by authors named "K Hacker"

Importance: Cigarette companies have been introducing synthetic cooling agent menthol-mimicking cigarettes into the US marketplace as menthol cigarette bans are implemented. These cigarettes may reduce the public health benefits of menthol cigarette bans.

Objective: To examine the epidemiology of the use of synthetic cooling agent menthol-mimicking cigarettes among adults in the US.

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  • Many individuals in healthcare settings, particularly those with gastrointestinal (GI) issues, have histories of trauma that can affect their health and interactions with medical professionals.* -
  • The study aimed to improve understanding of trauma's impact on GI patients and to develop effective strategies for healthcare providers to respond to trauma-related distress.* -
  • Innovative programs were created to help healthcare personnel recognize trauma effects, respond appropriately during patient interactions, and ultimately enhance the overall healthcare experience for GI patients.*
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Purpose Of Review: The Cancer Genome Atlas identified four distinct molecular subtypes of endometrial cancer (EC): POLE mutated, mismatch repair deficient (dMMR), copy number low, and copy number high. The goal of this review is to summarize the profound clinical implications of molecular subtyping, particularly in guiding treatment decisions for dMMR and microsatellite instability high (MSI-H) EC.

Recent Findings: Clinical trials have demonstrated the remarkable efficacy of immunotherapy in dMMR/MSI-H EC tumors.

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  • The study investigates the connection between social determinants of health (SDOH) and health-related social needs (HRSN) with chronic diseases among American adults using data from the 2022 Behavioral Risk Factor Surveillance System (BRFSS).
  • Findings reveal that a significant portion (66.3%) of participants had chronic diseases and 59.4% experienced adverse SDOH/HRSN, indicating higher prevalence of these social factors among those with chronic conditions, excluding cancer.
  • The research suggests that healthcare providers and public health systems should account for SDOH/HRSN when addressing treatment and prevention strategies for chronic diseases, particularly in communities that face higher rates of these conditions.
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Background: Overcoming the heterogeneous mechanisms of metastasis and chemoresistance will improve outcomes for women with tubo-ovarian carcinomas (TOCs). CD44 expression has been shown to be associated with poor prognosis and advanced disease in TOCs. In addition, studies have shown a link between chemoresistance and CD44 pathways.

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