Publications by authors named "K H Xuan"

The periodontal tissue comprises alveolar bone, cementum, and periodontal ligament (PDL), forming a highly hierarchical architecture. Although current therapies could regenerate the hard tissue well, the simultaneous reconstruction of hard and soft tissue remains a great clinical challenge with the major difficulty in highly orientated PDL regeneration. Using the unidirectional freeze-casting method and biomimetic mineralization technique, we construct a hierarchical bilayer scaffold with the aligned chitosan scaffold with ZIF-8 resembling PDL, and intrafibrillarly mineralized collagen resembling alveolar bone.

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A modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) -LC-MS/MS method was developed for the determination of hexachlorophene in fruits and vegetables. Samples were extracted by acetonitrile and then salted with an acetate buffer system. Extractants neutral alumina (Al-N), strong cation exchange silica gel bonded adsorbent (SCX) and graphitized carbon black (GCB) were used for sample purification.

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Article Synopsis
  • - Zimmermann-Laband Syndrome (ZLS) is a rare genetic disorder primarily characterized by gingival fibromatosis and underdeveloped fingernails and toenails, linked to specific gene mutations.
  • - A case study presented a 2-year-old patient with severe gingival enlargement and nail hypoplasia, where an initial diagnosis of ZLS was confirmed through genetic sequencing.
  • - Treatment involved surgical procedures to reduce gingival overgrowth, resulting in improved oral function and aesthetics, while follow-up showed mild recurrence, highlighting the importance of genetic testing and timely intervention for ZLS.
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Harnessing the developmental events of mesenchymal condensation to direct postnatal dental stem cell aggregation represents a cutting-edge and promising approach to tooth regeneration. Tooth avulsion is among the most prevalent and serious dental injuries, and odontogenic aggregates assembled by stem cells from human exfoliated deciduous teeth (SHED) have proven effective in revitalizing avulsed teeth after replantation in the clinical trial. However, whether and how SHED aggregates (SA) communicate with recipient components and promote synergistic tissue regeneration to support replanted teeth remains elusive.

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