The future of lactoferrin: A closer look at LipoDuo technology.

Background: Lactoferrin (Lf), a multifunctional glycoprotein known for its roles in immune modulation, iron metabolism, and antimicrobial activity, has limited therapeutic efficacy due to poor bioavailability. Liposomal encapsulation of lactoferrin (LLf) offers a potential solution by improving its stability, absorption, and sustained release, making it a promising candidate for various clinical applications. This study aims to compare the effectiveness of LLf and plain Lf in cellular uptake, proliferation, and wound healing using HEK-293T and Caco-2 cell lines.

Promotion of cellular differentiation and DNA repair potential in brain cancer cells by Shankhpushpi, (Clitoria ternatea L.) with rasayana properties in vitro.

Background: Brain ageing is accompanied by the diminution of neuronal plasticity, which is correlated with the inability to respond to loss of memory, various stress-induced stimuli, and increased risk of neurodegenerative disorders. In the recent past, plant based herbal medicines are of interest over synthetic drugs for therapeutic purposes due to lower side effects. The Indian traditional medicine Ayurveda describes several herbal remedies, such as rasayana (elixirs for rejuvenation), to treat many age-related diseases.

Adjunctive Mantram Repetition Program to Promote Lifestyle Modifications for Managing Impaired Glucose Tolerance: A Case Report from the USA.

We report the case of a 63-year-old man with impaired fasting glucose who was unable to lose weight, engage in exercise or omit refined carbohydrates from his diet until he initiated the Mantram Repetition Program (MRP). Four months following implementation, the patient had lost weight and fasting glucose levels decreased to near normal. These parameters continued to improve at nine months.

Social network analysis as a new tool to measure academic impact of physicians.

Introduction: H-index is a widely used metric quantifying a researcher's productivity and impact based on an author's publications and citations. Though convenient to calculate, h-index fails to incorporate collaborations and interrelationships between physicians into its assessment of academic impact, leading to limited insight into grouped networks. We present social network analysis as a tool to measure relationships between physicians and quantify their academic impact.

Energy of Functional Brain States Correlates With Cognition in Adolescent-Onset Schizophrenia and Healthy Persons.

Adolescent-onset schizophrenia (AOS) is relatively rare, under-studied, and associated with more severe cognitive impairments and poorer outcomes than adult-onset schizophrenia. Neuroimaging has shown altered regional activations (first-order effects) and functional connectivity (second-order effects) in AOS compared to controls. The pairwise maximum entropy model (MEM) integrates first- and second-order factors into a single quantity called energy, which is inversely related to probability of occurrence of brain activity patterns.